• Chromatography, electrophoresis, instrumentations

• Multi-dimensional HPLC and MS technologies

• Proteomic analysis and disease biomarker discovery

• Traditional Chinese medicines and environmental analysis

Xiangmin Zhang is Professor of Analytical Chemistry. He has the secondary appointment in Institutes of Biomedical Sciences at Fudan University. He was working in National Chromatographic Research Center, Chinese Academy of Sciences from 1986 to 1994. He did a post-doctoral in Fudan University 1994-1995. He became an associate professor of Fudan University 1996 and full professor in 1999. In 1996-1997, he was a Guest Professor in Tuebingen University in Germany; from 2004 to 2005, he was a Visiting Professor in the National Research Center of Environment and Health in Germany. He is the Editorial Board of PROTEOMICS, Anal Bioanal Chem, and the Chinese Journal of Chromatography.

• In 2006, the first prize of natural science, Ministry of Education.

• In 2012, the second prize of natural science, Ministry of Education.

1983, his M.Sc. degree from Dalian University of Technology in 1986, and his Ph.D. in Dalian Institute of Chemical Physics, Chinese Academy of Sciences in 1994.f natural science, Ministry of Education.

Teaching: “Advanced Instrumental Analysis”, “Chromatographic Analysis”, “Theoretical Foundation of Chromatography”, “Electrophoresis and Its Application to Biology”, “Methodology on Scientific Instrumentation”, and “Modern Topics of Chemistry—Bioseparation”.

1. Xueyang Zhang, Shaochun Zhu, Ya Xiong, Chunhui Deng, and Xiangmin Zhang, Development of a MALDI-TOF MS Strategy for the High-Throughput Analysis of Biomarkers: On-Target Aptamer Immobilization and Laser-Accelerated Proteolysis Angew. Chem. Int. Ed. 2013, 52, 6055-6058.

2. Junyan Liu, Yang Liu, Mingxia Gao and Xiangmin Zhang, An accurate proteomic quantification method: Fluorescence labeling absolute quantification (FLAQ) using multidimensional liquid chromatography and tandem mass spectrometry Proteomics 2012, 12, 2258–2270

3. Shaochun Zhu, Xueyang Zhang, Mingxia Gao, Guangfeng Hong, Guoquan Yan and Xiangmin Zhang, Developing a strong anion exchange/RP (SAX/RP) 2-DLC system for high-abundance proteins depletion in human plasma Proteomics 2012, 12, 1–14

4. Qian Tao, Qian Wu, Xiangmin Zhang, A Thermal Expansion Pump for Capillary High Performance Liquid Chromatography Anal. Chem. 2010, 82(3), 842-847

5. Jia Tang, Yingchao Liu, Dawei Qi, Guoping Yao, Chunhui Deng and Xiangmin Zhang, On-plate-selective enrichment of glycopeptides using boronic acid-modified gold nanoparticles for direct MALDI-QIT-TOF MS analysis Proteomics 2009, 9, 5046–5055

6.  Shuang Lin, Guoping Yao, Dawei Qi, Yan Li, Chunhui Deng, Pengyuan Yang, and, Xiangmin Zhang, Fast and Efficient Proteolysis by Microwave-Assisted Protein Digestion Using Trypsin-Immobilized Magnetic Silica Microspheres Anal. Chem. 2008, 78(22), 7828-7840

7.  Mingxia Gao, Chunhui Deng, Wenjia Yu, Yang Zhang, Pengyuan Yang and Xiangmin Zhang, Large scale depletion of the high-abundance proteins and analysis of middle- and low-abundance proteins in human liver proteome by multidimensional liquid chromatography Proteomics 2008, 8, 939–947

8.  Yan Li, Dawei Qi, Chunhui Deng, Pengyuan Yang, and Xiangmin Zhang, Cerium Ion-Chelated Magnetic Silica Microspheres for Enrichment and Direct Determination of Phosphopeptides by Matrix-Assisted Laser Desorption Ionization Mass Spectrometry Journal of Proteome Research 2008, 7, 1767–1777 1767

9. Weiqiang Hao, Xiangmin Zhang, Fengli Hu, Analysis of the Ideal Model for a Single-component in Preparative Gradient Elution Chromatography Anal. Chem. 2007, 79, 2507-2517

10. Xiuqing Xu, Chunhui Deng, Mingxia Gao, Wenjia Yu, Pengyuan Yang, Xiangmin Zhang , Synthesis of Magnetic Microspheres with Immobilized Metal Ions for Enrichment and Direct Determination of Phosphopeptides by MALDI-TOF-MS/MS Adv. Mater. 2006, 18, 3289-3293