Wan LiOrganic Chemistry, Associate Professor
Office Location:Engineering Center of Catalysis and Synthesis for Chiral Molecules Shanghai Engineering Center of Industrial Asymmetric Catalysis for Chiral Drugs

  • Research Interests

  • Academic Appointments

  • Prize and Awards

  • Biography

  • Teaching

  • Key Publications

  • Flow Chemistry, Microreactor

  • Asymmetric total synthesis of natural products and pharmaceuticals

  • C-H bond functionalization

  • 2022.01-NowAssociate Professor, Department of Chemistry, Fudan University

  • 2021.09-2021.12Associate Professor, School of Chemical Engineering, East China University of Science and Technology

  • 2017.10-2021.08Lecturer, School of Chemical Engineering, East China University of Science and Technology

  • 2014.07-2017.09Lecturer, College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University

  • 2012.09-2013.09Visiting Ph.D. Student in Organic Chemistry, The Scripps Research Institute (CA),Advisor: Prof. Jin-Quan Yu

  • 2009.09-2014.06Ph.D. in Applied Chemistry, Nanjing University of Science and Technology, Advisor: Prof. Chun Cai

  • 2005.09-2009.06B.Sc. in Pharmaceutical Engineering, Nanjing University of Science and Technology

    Organic Synthesis-II

1. L. Wan, M. F. Jiang, D. Cheng, M. J. Liu, F. E. Chen.Continuous flow technology-a tool for safer oxidation chemistry. React. Chem. Eng.2022, DOI: 10.1039/d1re00520k.

2. L. Zhang, X. F. Bo, H. L. Yao, M. M. Mao, L. Wan,* Z. Xin*. Zinc-catalyzed alkylation of aromatic amines in continuous flow. Org. Process Res. Dev.2020, 24, 2078-2084.

3. K. Qiao, D. Zhang, K. Zhang, X. Yuan, M. W. Zheng, T. F. Guo, Z. Fang, L. Wan*, K. Guo*. Iron(II)-catalyzed C-2 cyanomethylation of indoles and pyrroles via direct oxidative crossdehydrogenative coupling with acetonitrile derivatives. Org. Chem. Front.2018, 5, 1129-1134.

4. L.Wan, K.Qiao, X.Yuan, M. W.Zheng, B. B.Fan, Z. C.Di, D.Zhang, Z.Fang, K.Guo*. Nickel-catalyzed regioselective C-H bond mono- and bis-nitration of aryl oxazolines with TBN as nitro source. Adv. Syn. Cat.2017, 359, 2596-2604.

5. L. Wan, X. N.Sun, S. J.Shi, J. W.Zhang, X.Li, Z. J.Li, K.Guo*. An efficient synthesis of N-substituted phthalimides using SiO2-tpy-Nb as heterogeneous and reusable catalyst. Catal. Commun.2017, 88, 30-34.

6. L. Wan, W. T.Zhu, K.Qiao, X. N.Sun, Z.Fang, K.Guo*. C3 Alkylation of indoles catalyzed by carbocations under continuous-flow conditions. Asian J. Org. Chem.2016, 5, 920-926.

7. Y. B. Wu, G. P. Lu, B. J. Zhou, M. J. Bu, L. Wan, Chun Cai. Visible-light-initiated difluoromethylation of arene diazonium tetrafluoroborates. Chem. Commun. 2016, 52, 5965-5968.

8. G. Li, L. Wan, G. F. Zhang, D. Leow, J. Spangler, J.-Q. Yu. Pd(II)-Catalyzed C−H functionalizations directed by distal weakly coordinating functional groups. J. Am. Chem. Soc.2015, 137, 4391-4397.

9. L. Wan, N. Dastbaravardeh, G. Li, J.-Q. Yu. Cross-coupling of remote meta-C–H bonds directed by an U-shaped template. J. Am. Chem. Soc. 2013, 135, 18056-18059.

10. G. Li, D. Leow, L. Wan, J.-Q. Yu. Ether-directed ortho-C–H olefination with a palladium(II)/monoproctected amino acid catalyst. Angew. Chem., Int. Ed.2013, 52, 1245-1247.

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