Liu XiaowenBiopharmaceutics, Associate professor

Office Location: Fudan University-DSM Joint Laboratory
Tel: 15112131663

  • Research interests

  • Academic Appointments

  • Prizes and awards

  • Biography

  • Teaching

  • Key Publications

  • Protein engineering

  • Solubility enhancement of poorly water-soluble drugs

  • 2022.10-        Associate professor, Department of Chemistry, Fudan University

  • 2020.10-2022.9   Associate professor, School of Medicine, Jinan University, Guangzhou

  • 2017.3-2020.9    Associate research fellow, School of Medicine, Jinan University, Guangzhou

  • 2012.11-2016.11  PhD, Department of Pharmacy, University of Munich

  • 2009.9-2012.6    MSc, Institute of Functional Nano & Soft Materials, Soochow University

  • 2009.3-2009.6    Research engineer, Suzhou GenePharma Co.,Ltd

  • 2008.6-2008.12   Research engineer, Dongguan Wande Electronics Co., Ltd

  • 2004.9-2008.6    BSc, School of Environment and Chemical Engineering, Nanchang Hangkong University

  1. X. Xin, Y. Liu, L. Guo, H.Wang, D. Lu, Y. Chang, M. Wan, Y. Zhang, Y. Shan, Q. Zhang, X. Liu*, F. Gao*. Improvement of B cell responses by an HIV-1 amphiphilic polymer nanovaccine. Nano Lett., 2023, 23, 9, 4090–4094

  2. X. Liu*, L. Zhao, B. Wu, F. Chen*. Improving solubility of poorly water-soluble drugs by protein-based strategy: a review. Int. J. Pharm., 2023, 634,122704.    

  3. X. Xin, J. Chen, L. Chen, J. Wang, X. Liu*, F. Chen*. Lyophilized insulin micelles for long-term storage and regulation of blood glucose for preventing hypoglycemia. Chem. Eng.J., 2022, 435, 134929. 

  4. P. Zhou, X. Zhang, X. Xin, J. Yang, Q. Pan, C. Liu, Y. Liu, X. Yu, Z. Li*, G. Jiao*, X. Liu *.Click chemistry-conjugated protein-drug micelles with anti-ferroptotic and anti-inflammatory properties promote regeneration in spinal cord injury. Chem. Eng.J., 2022, 428, 132118.  

  5. X. Zhang, P. Zhou, S. Zhuo, F. Zhang, J. Yu, X. Liu*. Protein nanogels with enhanced pH-responsive dynamics triggered by remote NIR for systemic protein delivery and programmable controlled release. Int. J. Pharm., 2021, 605, 120833.   

  6. X. Xin, Y. Xu, H. Shi, X. Liu*. General method to stabilize mesophilic proteins in hyperthermal water. iSciecne, 2021, 24 (5), 102503.    

  7. X. Xin, Z. Zhang, X. Zhang, J. Chen, X. Lin*, P. Sun*, X. Liu*. Bioresponsive nanomedicines based on dynamic covalent bonds. Nanoscale, 2021, 13 (27), 11712-11733.   

  8. X. Liu, C. Wang *, Z. Liu *. Protein‐Engineered Biomaterials for Cancer Theranostics. Adv. Healthcare Mater., 2018, 7(20), 1800913.   

  9. X. Liu#, P. Zhang#, W. Rödl, K. Maier, U. Lächelt, E. Wagner*. Towards artificial immunotoxins: traceless reversible conjugation of RNase A with receptor targeting and endosomal escape domains. Mol. Pharm., 2017, 14 (5), 1439-1449. 

  10. X. Liu, P. Zhang, D. He, W. Rodl, T. Preiß, J. O.Radler, E. Wagner, U. Lächelt*. pH-reversible cationic RNase A conjugates for enhanced cellular delivery and tumor cell killing. Biomacromolecules, 2016, 17(1), 173-182.

  11. X. Liu, H. Tao, K. Yang, S. Lee and Z. Liu*. Optimization of Surface Chemistry on Single-Walled Carbon Nanotubes for in vivo Photothermal Ablation of Tumors. Biomaterials, 2011, 32 (1), 144-151.

Address: Chemistry Building, Department of Chemistry, Fudan University
2005 Songhu Road, Yangpu District, Shanghai 200438, China  Tel: 86-21-31242791
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