Liang Zhang

Inorganic Chemistry

Associate Professor

  zhangliang@chem.ecnu.edu.cn

  Chemistry Building

  (086)13248015871

  http://www.chemnanotopology.com//

Biography

  • 2008-2012  B.Sc. Department of Chemistry, Fudan University, Shanghai, China.

  • 2012-2015  M.Sc. Department of Chemistry, Fudan University, Shanghai, China.
    Advisor: Professor Zhan-Ting Li and Professor Dan-Wei Zhang

  • 2015-2018  Ph.D. School of Chemistry, The University of Manchester, Manchester, UK.
    Advisor: Professor David A. Leigh (FRS)

  • 2018-2019  Postdoctoral Fellowship & Team Leader of Leigh ECNU Research LabSchool of Chemistry, The University of Manchester, Manchester, UK.

  • 2020-2025  Zijiang Outstanding Young Professor, School of Chemistry and Molecular Engineering East China Normal University, Shanghai, China.

  • 2026-    Associate Professor, School of Chemistry, Fudan University, Shanghai, China.

Academic Appointments

  • Advisory Board of Chemical Science

  • Advisory Board of Chem  

  • Young Editorial Board Chinese Chemical Letters

Prizes and awards

  • The Sessler Early Career Researcher Prize (2025)  

  • Chinese Scientists with Cell Press Best Paper Award and Author Award (2023)   

  • Shanghai S&T 35U35 (S&T35) (2023)   

  • CCS Physical Organic Chemistry Young Investigator Award (2023)   

  • Royal Society of Chemistry Horizon Prize: Perkin Prize in Physical Organic Chemistry (2023)   

  • National Young Talent (2020-2023)   

  • Chinese Government Award for Outstanding Self-financed Student Abroad (2019)   

  • CAS Future Leader (2019)   

  • Finalist for Reaxys PhD Prize (2019)   

  • Manchester Doctoral College Best Outstanding Output Award, The University of Manchester (2019)   

  • Outstanding Achievement Award Spring, School of Chemistry, The University of Manchester (2019)   

  • RSC Biological and Medicinal Chemistry Sector (RSC-BMCS) International Travel Prize (2019)   

  • RSC Macrocyclic and Supramolecular Chemistry (RSC-MASC) PhD Thesis Award (2018)

Research Interests

  • Developing synthetic approaches / techniques to realise efficient control over the functionalities of topologically complex molecules

  • Probing the dynamics and mechanical response of interlocked / entangled molecules by single-molecule techniques

  • Introducing the topological theory and information transfer approach in the design and synthesis of entangled / woven polymers

Key Publications

  • Yang, R.; Zhao, X.; Zhang, Z.-H.*; Zhang, L.* Inducing chiral order in synthetic knotted system. Chem2025, doi:10.1016/j.chempr.2025.102855.

  • Chen, S.; Zhang, Z.-H.; Li, Y.; Chen, Y.; Yang, J.*; He, X.*; Zhang, L.* Implications of weaving pattern on the material properties of two-dimensional molecularly woven fabrics. Matter2025, 8, 102050. Highlighted by: Matter ‘Weave polymers with helical chirality’ (Preview), Kim, J. Matter 2025, 8, 102223.

  • Du, C.; Padgham, A. C.; Slater, A. G.*; Zhang, L.* Efficient flow-synthesis of a Star of David [2]catenane and a pentafoil knot. Chem2025, 11, 102328.

  • Zhou, Q.; Dong, X.; Chi, G.; Cao, X.-Y.*; Zhang, N.; Wu, S.; Ma, Y.; Zhang, Z.-H.*; Zhang, L.* Cinquefoil knot possessing dynamic and tunable metal coordination. J. Am. Chem. Soc. 2024, 146, 22405-22412. Highlighted by: Chem ‘Post-synthetic tuning of metal coordination on entangled scaffolds’ (Preview), Domoto, Y. Chem2024, 10, 2933-2934.;Sci. China Chem. ‘Knotting ligands to control metal coordination geometry’ (Highlight), Cougnon, F. B. L. Sci. China Chem. 2025, 68, 403-404.; ChemistryViews ‘Molecular knots tied with different metal ions’ 8th Aug.  

  • Chen, S.; Katsonis, N.*; Leigh, D. A.*; Patanapongpibul, M.; Ryabchun, A.; Zhang, L.* Changing liquid crystal helical pitch with a reversible rotaxane switch. Angew. Chem. Int. Ed. 2024, 63, e202401291.

  • Zhang, Z.-H.; Zhou, Q.; Li, Z.; Zhang, N.; Zhang, L.* Completely stereospecific synthesis of a molecular cinquefoil (51) knot. Chem2023, 9, 847-858. Back to Back Articles – Featured on Cover of Chem & 2023 Chinese Scientists with Cell Press Best Paper Award (10 papers across all cell press journals in physical science discipline) & Highlighted by: Chem ‘Stereoselective synthesis of topologically chiral molecular entanglements’ (Preview), Lewis, J. E. M. Chem 2023, 9, 762-764.; Nat. Sci. Rev. ‘Making chiral molecular knots and links stereospecifically’ (Highlight), Stoddart, J. F. et al. Nat. Sci. Rev. 2023, 10, nwad041.

  • Feng, H.-N.†; Sun, Z.†; Chen, S.; Zhang, Z.-H.; Li, Z.; Zhong, Z.; Sun, T.; Ma, Y.; Zhang, L.* A Star of David [2]catenane of single handedness. Chem 2023, 9, 859-868. Back to Back Articles. 2023 Chinese Scientists with Cell Press Author Award.

  • Calvaresi, M.; Duwez, A.-S.*; Leigh, D. A.*; Sluysmans, D.; Song, Y.; Zerbetto, F.*; Zhang, L.* Mechanical tightening of a synthetic molecular knot. Chem 2023, 9, 65-75. – Featured on Cover of Chem & Highlighted by: Nature ‘Tied up but resilient: synthetic knots show their strength’ 12th Jan 2023.

  • Chen, S.; Su, D.; Jia, C.; Li, Y.; Li, X.; Guo, X.*; Leigh, D. A.*; Zhang, L.* Real-time observation of the dynamics of an individual rotaxane molecular shuttle using a single molecule junction. Chem2022, 8, 243-252.

  • Zhang, Z.-H.; Andreassen, B. J.; August, D. P.; Leigh, D. A.*; Zhang, L.* Molecular weaving. Nature Mater. 2022, 21, 275-283. – Featured on Cover of Nature Materials.