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方彩云分析化学,副教授,博士生导师

  • 研究兴趣

  • 学术任职

  • 获奖情况

  • 学习工作经历

  • 授课情况

  • 代表性论文或专著

蛋白质组学方法学及其在生物医学中的应用研究,重点包括以下研究内容:

  • 发展低丰度和翻译后修饰(如棕榈酰化、糖化等)蛋白质的选择性分离富集以及定性定量分析新方法;

  • 蛋白质组学技术在重大疾病(如病毒性肝炎、心血管疾病、癌症等)发生发展机制与诊断中的应用研究。



  • 2002-9至2005-7      复旦大学化学系   博士

  • 1999-9至2002-7      中南大学化学化工学院   硕士

  • 1995-9至1999-7      中南工业大学化学系   学士

  • 2005-7~至今   复旦大学化学系, 讲师,副教授

  • 2009~2011   美国加州大学洛杉矶分校,访问学者

  • 本科生基础理论课《分析化学》(必修);

  • 本科生基础实验课《无机化学和化学分析实验I和II》、《仪器分析与物理化学实验》和《分析化学实验》(必修).

  1. Shen, Yuan#; Zheng, Liangliang#; Fang, Caiyun#; Xu, Yaoyao; Wang, Chao; Li, Jintao; Lei, Mingzhu; Yin, Miao; Lu, Haojie*; Lei, Qunying*; Qu, Jia*; ABHD7-mediated depalmitoylation of lamin A promotes myoblast differentiation, Cell Reports, 2024, 43: 113720.

  2. Wu, Roujun; Ji, Guanghui; Chen, Weiyu; Zhang, Lei; Fang, Caiyun*; Lu, Haojie*; Simultaneous and site-specific profiling of heterogeneity and turnover in protein S-acylation by intact S-acylated peptides analysis with a cleavable bioorthogonal tag, Analyst, 2024, 149(4): 1111-1120.

  3. Ji, Guanghui, Wu, Roujun; Zhang, Lei; Yao, Jun; Zhang, Cheng; Zhang, Xiaoqin; Liu, Zhiyong; Liu, Yang; Wang, Ting; Fang, Caiyun*; Lu, Haojie*; Global analysis of endogenously intact Sacylated peptides reveals localization differentiation of heterogeneous lipid chains in mammalian cells, Analytical Chemistry, 2023, 95: 13055-13063.

  4. Fang, Caiyun*; Zhang, Xiaoqin; Lu, Haojie*; Quantification of protein palmitoylation by cysteine-SILAC, Chapter 5 in SILAC Methods and Protocols, Methods in Molecular Biology (Springer Protocols), 2023 (ISBN978-1-0716-2862-1), Humana Press.

  5. Chen, Weiyu; Ji, Guanghui; Wu, Roujun; Fang, Caiyun*; Lu, Haojie*; Mass spectrometry-based candidate substrate and site identification of PTM enzymes, Trends in Analytical Chemistry, 2023, 160: 116991.

  6. Wu, Linlin; Fei, Weiwei; Liu, Zhiyong; Zhang, Lei; Fang, Caiyun*; Lu, Haojie*; Specific and Reversible Enrichment of Early-Stage Glycated Proteome Based on Thiazolidine Chemistry and Palladium-Mediated Cleavage, Analytical Chemistry, 2022, 94(13): 5213-5220.

  7. Fang, Caiyun; Lu, Haojie; Clinical Applications, Chapter 6 in Mass Spectrometry–Based Glycoproteomics and Its Clinic Application, 2021, CRC Press.

  8. Du, Xiaoxian; Lu, Jingtian; Yang, Lijun; Bao, Huimin; Zhang, Lei; Yan, Guoquan; Fang, Caiyun*; Lu, Haojie*; Rapid and Easy Enrichment Strategy for Naturally Acetylated N Termini Based on LysN Digestion and Amine-Reactive Resin Capture, Analytical Chemistry, 2020, 92(12): 8315-8322.

  9. Zhang, Xiaoqin; Zhang, Yuting; Fang, Caiyun*; Zhang, Lei; Yang, Pengyuan; Wang, Changchun*; Lu, Haojie*; Ultra-deep palmitoylomics enabled by a dithiodipyridine functionalized magnetic nanoparticles, Analytical Chemistry, 2018, 90(10): 6161-6168. 

  10. Zhang, Xiaoqin; Zhang, Lei; Ji, Guanghui; Lei, Qunying; Fang, Caiyun*; Lu, Haojie*; Site-Specific Quantification of Protein Palmitoylation by Cysteine-Stable Isotope Metabolic Labeling, Analytical Chemistry, 2018, 90(17): 10543-10550.

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