Research Interests

• Asymmetric catalysis

• Catalytic reactions with earth-abundant transition metals

• Design and synthesis of novel chiral catalysts/ligands

Biography

• 2006.9-2010.6BSc, College of Chemistry and Material Science, Shandong Agriculture University

• 2011.9-2016.6PhD, School of Chemistry and Molecular Engineering, East China Normal University

• 2016.9-2018.9Postdoc, School of Chemistry and Molecular Engineering, East China Normal University

• 2018.9-2020.12Postdoc, Department of Chemistry, Fudan University

• 2021.1-Young Researcher, Department of Chemistry, Fudan University

Key Publications

1. L. Zhou,^† S. Li,^† (†: co-first author) B. Xu, D. Ji, L. Wu, Y. Liu, Z. Zhang and J. Zhang. Enantioselective Difunctionalization of Alkenes by Palladium-Catalyzed Heck/Sonogashira Sequence. Angew. Chem. Int. Ed. 59, 2769-2775 (2020).

2. H. Wang,^† H. Luo,^†Z. Zhang,^† (†: co-first author) W. Zheng, Y. Yin, H. Qian, J. Zhang, and S. Ma. Pd-Catalyzed Enantioselective Syntheses of Trisubstituted Allenes via Coupling of Propargylic Benzoates with Organoboronic Acids. J. Am. Chem. Soc. 142, 9763-9771 (2020).

3. R. Zhang, B. Xu, Z. Zhang and J. Zhang. Ming-Phos/Copper(I)- Catalyzed Asymmetric [3+2] Cycloaddition of Azomethine Ylides with Nitroalkenes. Acta Chim. Sinica 78, 245-249 (2020).

4. L. Zhou, B. Xu, D. Ji, Z. Zhang and J. Zhang. Ming-Phos/Gold(I)-Catalyzed StereodivergentSynthesis of Highly Substituted Furo[3,4-d][1,2]oxazines. Chin. J. Chem. 38, 577-582 (2020).

5. Z. Zhang,^† B. Xu,^† (†: co-first author) L. Wu, L. Zhou, D. Ji, Y. Liu, Z. Li, and J. Zhang. Palladium/XuPhos-Catalyzed Enantioselective Carboiodination of Olefin-Tethered Aryl Iodides. J. Am. Chem. Soc. 141, 8110-8115 (2019).

6. Z. Zhang, B. Xu, L. Wu, Y. Wu, Y. Qian, L. Zhou, Y. Liu, and J. Zhang. Enantioselective Dicarbofunctionalization of Unactivated Alkenes by Palladium-Catalyzed Tandem Heck/Suzuki Coupling Reaction. Angew. Chem. Int. Ed. 58, 14653-14659 (2019).

7. Y. Wu, B. Xu, B. Liu, Z. Zhang and Y. Liu. A new trifluoromethylated sulfonamide phosphine ligand for Ag(I)-catalyzed enantioselective [3+2] cycloaddition of azomethine ylides. Org. Biomol. Chem. 17, 1395-1401 (2019).

8. Z. Zhang,^† B. Xu,^† (†: co-first author) Y. Qian, L. Wu, Y. Wu, L. Zhou, Y. Liu, and J. Zhang. Palladium-Catalyzed Enantioselective Reductive Heck Reactions: Convenient Access to 3,3-Disubstituted 2,3-Dihydrobenzofuran. Angew. Chem. Int. Ed. 57, 10373-10377 (2018).

9. Shan Xu,^†Z. Zhang,^† (†: co-first author) B. Xu, B. Liu, Y. Liu, and J. Zhang. Enantioselective Regiodivergent Synthesis of Chiral Pyrrolidines with Two Quaternary Stereocenters via Ligand-Controlled Copper(I)-Catalyzed Asymmetric 1,3-Dipolar Cycloadditions. J. Am. Chem. Soc. 140, 2272-2283 (2018).

10. B. Xu,^† Z. Zhang,^† (†: co-first author) S. Xu, B. Liu, Y. Xiao, and J. Zhang. Copper(I)/Ming-Phos-Catalyzed Asymmetric Intermolecular [3+2] Cycloaddition of Azomethine Ylides with α‑Trifluoromethyl α, β‑Unsaturated Esters. ACS Catal. 7, 210-214 (2017).

11. Z. Zhang,^† B. Xu,^† (†: co-first author) S. Xu, H. Wu, and J. Zhang. Diastereo- and Enantioselective Copper(I)-Catalyzed Intermolecular [3+2] Cycloaddition of Azomethine Ylides with β-Trifluoromethyl β, β-Disubstituted Enones. Angew. Chem. Int. Ed. 55, 6324-6328 (2016).

12. Z. Zhang, P. Chen, W. Li, Y. Niu, X. Zhao, and J. Zhang. A New Type of Chiral Sulfinamide Monophosphine Ligands: Stereodivergent Synthesis and Application in Enantioselective Gold(I)-Catalyzed Cycloaddition Reactions. Angew. Chem. Int. Ed. 53, 4350-4354 (2014).