Research Interests

• Our research interests include the physical organic chemistry and the construction of functional supramolecular systems, particularly for their bio-mimicking applications as trans-membrane channels and biosensors

Prizes and awards

• 2005, Special Prize of President Scholarship for Postgraduate Students, CAS

• 2008, One Hundred Excellent Ph.D. Dissertations Award in China

• 2013, Chinese Chemical Society Prize for Young Scientists

Biography

• 09.1997-07.2001   Hubei University, B. S.

• 09.2001-07.2006   Shanghai Institute of Organic Chemistry, CAS, Ph.D.

• 09.2006-09.2008   The Scripps Research Institute, USA, Postdoc

• 10.2008-present    Fudan University, Associate Professor

Teaching

• Experimental Course for Synthetic Chemistry, for undergraduate students, 2009-2012

• Physical Organic Chemistry, for Ph.D. students, 2009-2014

Key Publications

1. Yong-Hong Fu, Yi-Fei Hu, Tao Lin, Guo-Wei Zhuang, Ying-Lan Wang, Wen-Xue Chen, Zhan-Ting Li, and Jun-Li Hou*, Constructing artificial gap junctions to mediate intercellular signal and mass transport, Nature Chem. 2024, 16, 1418-1426 (Highlight: Nature Chem. 2024, 16, 1387-1389).

2. Qi Xiao, Daoming Guan, Yong-Hong Fu, Ting Fan, Lei Zhang, Zhan-Ting Li, Yunxiang Zhang,* Yunfeng Wang,* and Jun-Li Hou*, Supramolecular Channels Assembled within Intercellular Gaps, J. Am. Chem. Soc.2024, 146, 22869-22873.

3. Zhao-Jun Yan, Ya-Wei Li, Maohua Yang, Yong-Hong Fu, Rongrong Wen, Wenning Wang, Zhan-Ting Li, Yunxiang Zhang,* and Jun-Li Hou*, Voltage-Driven Flipping of Zwitterionic Artificial Channels in Lipid Bilayers to Rectify Ion Transport, J. Am. Chem. Soc. 2021, 143, 11332-11336 (JACS Spotlights: J. Am. Chem. Soc. 2021, 143, 11275-11276).

4. Zhao-Jun Yan, Dongdong Wang, Zhongju Ye, Ting Fan, Gang Wu, Liyun Deng, Lu Yang, Binxiao Li, Jianwei Liu, Tonghui Ma, Chaoqing Dong, Zhan-Ting Li, Lehui Xiao,* Yunfeng Wang,* Wenning Wang,* and Jun-Li Hou*, Artificial Aquaporin That Restores Wound Healing of Impaired Cells, J. Am. Chem. Soc. 2020, 142, 15638-15643.

5. Min Zhang, Ping-Ping Zhu, Pengyang Xin, Wen Si, Zhan-Ting Li, Jun-Li Hou*, Synthetic Channel Specifically Inserts into the Lipid Bilayer of Gram-Positive Bacteria but not that of Mammalian Erythrocytes, Angew. Chem. Int. Ed. 2017, 56, 2999-3003.

6. Ge Su, Min Zhang, Wen Si, Zhan-Ting Li, Jun-Li Hou*, Directional Potassium Transport through a Unimolecular Peptide Channel, Angew. Chem. Int. Ed. 2016, 55, 14678-14682.

7. Wen Si, Pengyang Xin, Zhan-Ting Li, Jun-Li Hou*, Tubular Unimolecular Transmembrane Channels: Construction Strategy and Transport Activities, Acc. Chem. Res. 2015, 48, 1612-1619.

8. Wen Si, Zhan-Ting Li, Jun-Li Hou*, Voltage-Driven Reversible Insertion into and Leaving from a Lipid Bilayer: Tuning Transmembrane Transport of Artificial Channels, Angew. Chem. Int. Ed. 2014, 53, 4578-4581.

9. Lei Chen, Wen Si, Liang Zhang, Gangfeng Tang, Zhan-Ting Li, Jun-Li Hou*, Chiral Selective Transmembrane Transport of Amino Acids through Artificial Channels, J. Am. Chem. Soc. 2013, 135, 2152-2155.

10. Xiao-Bo Hu, Zhenxia Chen, Gangfeng Tang, Jun-Li Hou*, Zhan-Ting Li, Single-Molecular Artificial Transmembrane Water Channels, J. Am. Chem. Soc. 2012, 134, 8384-8387 (Highlights: C&EN, 2012, 90 (22), p10; Angew. Chem. Int. Ed. 2012, 51, 11674-11676).