师资队伍
化学生物学,分析化学
“瑞清”特聘讲席教授,博士生导师
核酸化学
DNA生物功能材料
先进肿瘤诊疗技术
合成生物学
《Advanced Functional Materials》编委(2023-)
《Chinese Chemical Letters》编委(2020-)
《Small Methods》客座编辑(2024)
《Chinese Journal of Chemistry》客座编辑(2024)
2022年国家杰出青年基金
2016年国家优秀青年基金
2015年国家海外高层次人才
1998-2002 华中科技大学化学系,学士
2002-2005 华中科技大学化学系,硕士
2005-2008 中国科学院国家纳米科学中心,博士
2008-2010 中国科学院苏州纳米所,助理研究员
2010-2014 美国康奈尔大学,博士后
2014-2015 荷兰奈梅亨大学,博士后
2015-2024 天津大学,教授
2024-至今 复旦大学,教授
DNA合成化学
核酸功能材料
Nachuan Song+, Hongjin Li+, Chi Yao*, Dayong Yang*, Dynamic Chemistry of DNA-Based Nanoassemblies in Living Cells, Accounts of Chemical Research, 2024, 57, 2763.
Sen Yang+, Junlin Wu+, Zhongyu Wang, Yu Cheng, Rui Zhang, Chi Yao*, Dayong Yang*, A Smart DNA Hydrogel Enables Synergistic Immunotherapy and Photodynamic Therapy of Melanoma. Angewandte Chemie International Edition, 2024, in press.
Nachuan Song+, Xiaoting Fan+, Xiaocui Guo+, Jianpu Tang, Hongjin Li, Ruoyu Tao, Fengqin Li, Junru Li, Dayong Yang*, Chi Yao*, Peifeng Liu*, A DNA/Upconversion Nanoparticle Complex Enables Controlled Co-Delivery of CRISPR-Cas9 and Photodynamic Agents for Synergistic Cancer Therapy. Advanced Materials, 2024, in press.
Yanfei Guo, Siqi Li, Zhaobin Tong, Jianpu Tang, Rui Zhang, Zhaoyue Lv, Nachuan Song, Dayong Yang*, Chi Yao*, Telomerase-Mediated Self-Assembly of DNA Network in Cancer Cells Enabling Mitochondrial Interference. Journal of the American Chemical Society, 2023, 145, 23859.
Nachuan Song+, Yiwen Chu+, Shuai Li, Yuhang Dong, Xiaoting Fan, Jianpu Tang, Yanfei Guo, Guangshuai Teng, Chi Yao*, Dayong Yang*, Cascade Dynamic Assembly/Disassembly of DNA Nanoframework Enabling the Controlled Delivery of CRISPR-Cas9 System. Science Advances, 2023, 9, eadi3602.
Zhaoyue Lv+, Mengxue Huang+, Jing Yang+, Peiran Li, Lele Chang, Qianyun Tang, Xiaojing Chen, Shengqi Wang*, Chi Yao*, Peifeng Liu*, Dayong Yang*, A Smart DNA-Based Nanosystem Containing Ribosome-Regulating siRNA for Enhanced mRNA Transfection. Advanced Materials, 2023, 35, 2300823.
Jianpu Tang+, Xuemei Jia+, Qian Li+, Zhen Cui, Aiqi Liang, Bin Ke, Dayong Yang*, Chi Yao*, A DNA-Based Hydrogel for Exosome Separation and Biomedical Applications. Proceedings of the National Academy of Sciences of the United States of America, 2023, 120, e2303822120.
Fengqin Li+, Junru, Li+, Weiqiang Yang+, Shuai Yang, Congshuo Chen, Ling Du, Junyang Mei, Qianyun Tang, Xiaojing Chen, Chi Yao, Dayong Yang*, Xiaolei Zuo*, Peifeng Liu*, Framework-Hotspot Enhanced Trans Cleavage of CRISPR-Cas12a for Clinical Samples Detection. Angewandte Chemie International Edition, 2023, 62, e202305536.
Chi Yao+*, Yuwei Xu+, Jianpu Tang+, Pin Hu, Hedong Qi, Dayong Yang*, Dynamic Assembly of DNA-Ceria Nanocomplex in Living Cells Generates Artificial Peroxisome. Nature Communications, 2022, 13, 7739.
Chi Yao+, Junhan Ou+, Jianpu Tang+, Dayong Yang*, DNA Supramolecular Assembly on Micro/Nanointerfaces for Bioanalysis. Accounts of Chemical Research, 2022, 55, 2043.
Yuhang Dong+, Feng Li+, Zhaoyue Lv, Shuai Li, Meihe Yuan, Nachuan Song, Jinqiao Liu, Dayong Yang*, Lysosome Interference Enabled by Proton-Driven Dynamic Assembly of DNA Nanoframeworks inside Cells. Angewandte Chemie International Edition, 2022, 61, e202207770.
Feng Li+, Yujie Liu+, Yuhang Dong, Yiwen Chu, Nachuan Song, Dayong Yang*, Dynamic Assembly of DNA Nanostructures in Living Cells for Mitochondrial Interference. Journal of the American Chemical Society, 2022, 144, 4667.
Huaixin Zhao+, Linghui Li+, Feng Li*, Chunxia Liu, Mengxue Huang, Jiao Li, Feng Gao, Xinhua Ruan, Dayong Yang*, An Energy-Storing DNA-Based Nanocomplex for Laser-Free Photodynamic Therapy. Advanced Materials, 2022, 34, 2109920.
Feng Li+, Nachuan Song+, Yuhang Dong, Shuai Li, Linghui Li, Yujie Liu, Zhemian Li, Dayong Yang*, A Proton-Activatable DNA-Based Nanosystem Enables Co-Delivery of CRISPR/Cas9 and DNAzyme for Combined Gene Therapy. Angewandte Chemie International Edition, 2022, 61, e202116569.
Chi Yao+, Hedong Qi+, Xuemei Jia, Yuwei Xu, Zhaobin Tong, Zi Gu, Dayong Yang*, A DNA Nanocomplex Containing Cascade DNAzymes and Promoter-Like Zn-Mn-Ferrite for Combined Gene/Chemo-Dynamic Therapy. Angewandte Chemie International Edition, 2022, 61, e202113619.
Jinpeng Han, Yanfei Guo, Hang Wang, Kunyu Zhang, Dayong Yang*, Sustainable Bioplastic Made from Biomass DNA and Ionomers. Journal of the American Chemical Society, 2021, 143, 19486.
Chi Yao+, Chenxu Zhu+, Jianpu Tang, Junhan Ou, Rui Zhang, Dayong Yang*, T Lymphocyte-Captured DNA Network for Localized Immunotherapy. Journal of the American Chemical Society, 2021, 143, 19330.
Feng Li+, Zhaoyue Lv+, Xue Zhang, Yuhang Dong, Xiaohui Ding, Zhemian Li, Shuai Li, Chi Yao, Dayong Yang*, Supramolecular Self-Assembled DNA Nanosystem for Synergistic Chemical and Gene Regulations on Cancer Cells. Angewandte Chemie International Edition, 2021, 60, 25557.
Chi Yao+, Rui Zhang+, Jianpu Tang, Dayong Yang*, Rolling Circle Amplification (RCA)-Based DNA Hydrogel. Nature Protocols, 2021, 16, 5460.
Feng Li+, Wenting Yu+, Jiaojiao Zhang, Yuhang Dong, Xiaohui Ding, Xinhua Ruan, Zi Gu, Dayong Yang*, Spatiotemporally Programmable Cascade Hybridization of Hairpin DNA in Polymeric Nanoframework for Precise siRNA Delivery. Nature Communications, 2021, 12, 1138.
Xiaocui Guo+, Feng Li+, Chunxia Liu, Yi Zhu, Nannan Xiao, Zi Gu, Dan Luo, Jianhui Jiang, Dayong Yang*, Construction of Organelle-Like Architecture by Dynamic DNA Assembly in Living Cells. Angewandte Chemie International Edition, 2020, 59, 20651.
Yuhang Dong+, Chi Yao+, Yi Zhu, Lu Yang, Dan Luo, Dayong Yang*, DNA Functional Materials Assembled from Branched DNA: Design, Synthesis and Applications. Chemical Reviews, 2020, 120, 9420.
Dong Wang, Jinhui Cui, Mingzhe Gan, Zhaohui Xue, Jing Wang, Peifeng Liu, Yue Hu, Yehudah Pardo, Shogo Hamada, Dayong Yang*, Dan Luo*, Transformation of Biomass DNA into Biodegradable Materials from Gels to Plastics for Reducing Petrochemical Consumption. Journal of the American Chemical Society, 2020, 142, 10114.
Feng Li+, Shuai Li+, Xiaocui Guo, Yuhang Dong, Chi Yao, Yangping Liu, Yuguang Song, Xiaoli Tan, Lizeng Gao, Dayong Yang*, Chiral Carbon Dots Mimicking Topoisomerase I to Enantioselectively Mediate the Topological Rearrangement of Supercoiled DNA Enantioselectively. Angewandte Chemie International Edition, 2020, 59, 11087.
Chi Yao+, Han Tang+, Weijian Wu, Jianpu Tang, Weiwei Guo, Dan Luo, Dayong Yang*, Double Rolling Circle Amplification Generates Physically Cross-linked DNA Network for Stem Cell Fishing. Journal of the American Chemical Society, 2020, 142, 3422.
Jianpu Tang+, Chi Yao+, Zi Gu, Sunghwan Jung, Dan Luo, Dayong Yang*, Super-Soft and Super-Elastic DNA Robot with Magnetically Driven Navigational Locomotion for Cell Delivery in Confined Space. Angewandte Chemie International Edition, 2020, 59, 2490.
Xiaocui Guo+, Feng Li+, Lihui Bai, Wenting Yu, Xue Zhang, Yi Zhu, Dayong Yang*, Gene Circuit Compartment on Nanointerface Facilitatating Cascade Gene Expression. Journal of the American Chemical Society, 2019, 141, 19171.