朱灿

有机化学

青年研究员,博士生导师

zhucan@fudan.edu.cn

上海市杨浦区淞沪路2005号复旦大学江湾校区化学楼A5023室

https://www.x-mol.com/groups/CanZhu

研究兴趣

  • 过渡金属催化:新型配体和催化剂的设计与开发

  • 导向天然产物、药物分子的有机合成方法学研究

获奖情况

  • 2013年 “汪猷”优秀博士奖学金

  • 2014年 “M. Braun” 奖学金

  • 2016年 德国洪堡基金

  • 2019年 瑞典“Olle Engkvist”基金

学习工作经历

  • 2005.9-2009.7  中国科学技术大学化学系本科,获得理学学士学位

  • 2009.9-2014.7  中国科学院上海有机化学研究所研究生,获得理学博士学位

  • 2014.9-2016.8  瑞典斯德哥尔摩大学博士后

  • 2016.9-2018.6  德国明斯特大学博士后

  • 2018.7-2019.9  瑞典斯德哥尔摩大学研究员(researcher)

  • 2019.10-2020.9  瑞士巴塞尔大学博士后

  • 2020.11起  复旦大学化学系青年研究员

代表性论文或专著

  • T. Zhang, W. Wang, X. Lou†, Y. Peng, T. Cao, X. Sheng,* C. Zhu*, Anion-Assisted Copper/Chiral Diamine-Catalyzed Aerobic Oxi-dation for the Kinetic Dearomative Spirocyclization of Arenols. Angew. Chem. Int. Ed. 2025, e19818.  

  • K. Wang, Y. Peng, D. Lou, C. Zhu*, Cooperative Copper/Lipase Catalysis for the Chemoenzymatic Dynamic Kinetic Resolution (DKR) of Bis-(hetero)arenols. JACS Au 2025, 5, 5800−5812.  

  • J. Zhang, C. Zhu*, A Modular Three-Component Asymmetric Tsuji–Trost Reaction Enabled by Cooperative Palladium/Lewis Acid Catalysis. Angew. Chem. Int. Ed. 2025, e202512977.  

  • J. Zhang, K. Wang, C. Zhu*, Deracemization of Atropisomeric Biaryls Enabled by Copper Catalysis. JACS Au 2024, 4, 502−511.  

  • K. Wang, W. Wang, D. Lou, J. Zhang, C. Chi, J.-E. Bäckvall,* X. Sheng,* C. Zhu*, Overcoming the Limitations of Transition-Metal Catalysis in the Chemoenzymatic Dynamic Kinetic Resolution (DKR) of Atropisomeric Bisnaphthols. ACS Cent. Sci2024, 10, 2099−2110.  

  • D. Zhao, B. Xu, C. Zhu*, Migratory allylic arylation of 1,n-enols enabled by nickel catalysis. Nat. Commun. 2023, 14, 3308.  

  • C. Zhu*, J. Liu†, B. K. Mai, F. Himo*, J. E. Bäckvall*. Efficient Stereoselective Carbocyclization to cis-1,4-Disubstituted Heterocycles Enabled by Dual Pd/Electron Transfer Mediator (ETM) Catalysis. J. Am. Chem. Soc. 2020, 142, 5751−5759.  

  • C. Zhu†*, J. Liu†, M.-b. Li†, J.-E. Bäckvall*. Palladium-catalyzed oxidative dehydrogenative carbonylation reactions using carbon monoxide and mechanistic overviews. Chem. Soc. Rev. 2020, 49, 341−353.  

  • M. B. Li, D. Posevins, A. Geoffroy, C. Zhu*, J. E. Bäckvall*. Efficient Heterogeneous Palladium-Catalyzed Oxidative Cascade Reactions of Enallenols to Furan and Oxaborole Derivatives. Angew. Chem. Int. Ed. 202059, 1992−1996.  

  • C. Zhu†*, B. Yang†, B. K. Mai, S. Palazzotto, Y. Qiu, A. Gudmundsson, A. Ricke, F. Himo*, J. E. Bäckvall*. Highly Selective Palladium-Catalyzed Hydroborylative Carbocyclization of Bisallenes to Seven-Membered Rings. J. Am. Chem. Soc. 2018, 140, 14324−14333.  

  • C. Zhu, J. L. Schwarz, S. Cembellín, S. Greßies, F. Glorius*. Highly Selective Manganese(I)/Lewis Acid Cocatalyzed Direct C‒H Propargylation Using Bromoallenes. Angew. Chem. Int. Ed. 2018, 57, 437−441.  

  • B. Yang, Y. Qiu, T. Jiang, W. D. Wulff, X. Yin, C. Zhu*, J. E. Bäckvall*. Enantioselective Pd-Catalyzed Carbonylative Carbocyclization of Enallenes via Cross-Dehydrogenative Coupling with Terminal Alkynes: Efficient Construction of α-Chirality of Ketones. Angew. Chem. Int. Ed. 2017, 56, 4535−4539.  

  • C. Zhu, B. Yang†, Y. Qiu, J. E. Bäckvall*. Highly Selective Construction of Seven-Membered Carbocycles by Olefin-Assisted Palladium-Catalyzed Oxidative Carbocyclization–Alkoxycarbonylation of Bisallenes. Angew. Chem. Int. Ed. 2016, 55, 14405−14408.   

  • Y. Qiu, B. Yang, C. Zhu*, J. E. Bäckvall*. Palladium-Catalyzed Oxidative Carbocyclization-Borylation of Enallenes to Cyclobutenes. Angew. Chem. Int. Ed. 2016, 55, 6520−6524.  

  • B. YangC. Zhu, Y. Qiu, J. E. Bäckvall*. Enzyme- and Ruthenium-Catalyzed Enantioselective Transformation of α-Allenic Alcohols to 2,3-Dihydrofurans. Angew. Chem. Int. Ed. 2016, 55, 5568−5572.

  • C. Zhu, B. Yang, J. E. Bäckvall*. Highly Selective Cascade C‒C Bond Formation via Palladium-Catalyzed Oxidative Carbonylation-Carbocyclization-Carbonylation-Alkynylation of Enallenes. J. Am. Chem. Soc. 2015, 137, 11868−11871.  

  • C. Zhu, B. Yang, T. Jiang, J. E. Bäckvall*. Olefin-Directed Palladium-Catalyzed Regio-and Stereoselective Oxidative Arylation of Allenes. Angew. Chem. Int. Ed. 2015, 54, 9066−9069.  

  • C. Zhu, S. Ma*. Sc(OTf)3-Catalyzed Bicyclization of o-Alkynylanilines with Aldehydes: Ring-Fused 1,2-Dihydroquinolines. Angew. Chem. Int. Ed. 2014, 53, 13532−13535.  

  • C. Zhu, X. Zhang, X. Lian, S. Ma*. One-Pot Approach to Installing Eight-Membered Rings onto Indoles. Angew. Chem. Int. Ed. 2012, 51, 7817−7820.