ZHANG Guoting

Organic Chemistry,

Assistant Professor

guotingzhang@fudan.edu.cn

Research Interests

  • Electrochemical asymmetric catalysis

  • Total synthesis of natural products

  • Electrochemical biocatalysis

Biography

  • 2009.9-2013.6BSc, Department of Chemistry, Fuzhou University 

  • 2013.9-2018.6PhD, College of Chemistry and Molecular Science, Wuhan University 

  • 2018.8-2021.4Postdoctoral Fellowship, Stanford University, USA 

  • 2021.4-2024.12Postdoctoral Fellowship, École polytechnique fédérale de Lausanne (EPFL), Switzerland 

  • 2025.3-Assistant Professor, Department of Chemistry, Fudan University

Prizes and awards

  • 2018, The Top Ten Academic Stars of Wuhan University

Key Publications

  • G. Zhang, M. D. Wodrich, N. Cramer*, “Catalytic enantioselective reductive Eschenmoser-Claisen rearrangements”, Science, 383, 395-401 (2024).   

  • G. Zhang, N. Cramer*, “Reductive asymmetric aza-Mislow-Evans rearrangement by 1,3,2-diazaphospholene Catalysis”, Angew. Chem., Int. Ed. 62, e202301076 (2023).   

  • B. M. Trost*, G. Zhang,+ H. Gholami,+ D. Zell, “Total synthesis of Kadcoccinic Acid A trimethyl ester”, J. Am. Chem. Soc., 143, 12286-12293 (2021). (+Co-first author)   

  • B. M. Trost*, G. Zhang, “Ruthenium-catalyzed intermolecular coupling of vinylic 1,2-bisboronates with alkynes: stereoselective access to boryl-substituted homoallylic alcohols”, J. Am. Chem. Soc., 142, 7312-7316 (2020).   

  • G. Zhang, Y. Lin , X. Luo , X. Hu, C. Chen, A. Lei*, “Oxidative [4+2] annulation of styrenes with alkynes under external-oxidant-free conditions”, Nat. Commun. 9, 1225 (2018).   

  • G. Zhang, X. Hu, C-W Chiang, H. Yi, P. Pei, A. K. Singh, A. Lei*, “Anti-Markovnikov oxidation of β-alkyl styrenes with H2O as the terminal oxidant”, J. Am. Chem. Soc. 138, 12037-12040 (2016).   

  • G. Zhang, C. Liu, H. Yi, Q.Y. Meng, C. Bian, H. Chen, J.-X. Jian, L.-Z. Wu*, A. Lei*, “External oxidant-free oxidative cross-coupling: a photoredox cobalt-catalyzed aromatic C-H thiolation for constructing C-S bonds”, J. Am. Chem. Soc. 137, 9273-9280 (2015).   

  • X. Hu,+ G. Zhang,+ L. Nie, T. Kong and Aiwen Lei*, “Electrochemical oxidation induced intermolecular aromatic C-H imidation”, Nat. Commun. 10, 5467 (2019). (+Co-first author)   

  • X. Hu,+ G. Zhang,+ F. Bu, A. Lei*, “Photo-oxidation induced selective oxidative [4+2] imine/alkene annulation with H2 liberation”, Angew. Chem., Int. Ed. 57, 1286-1290 (2018). (+Co-first author)