Ying Zhang

Chemical Biology

Professor

  ying@fudan.edu.cn

   A4022, Chemistry Building

  021- 54237618

  

Research Interests

  • Mass spectrometry analysis methods for protein post-translational modifications (e.g. glycosylation et al.)

  • Mass spectrometry analysis methods for glycomics

  • Chemical proteomics and functional proteomics

  • Omics analysis methods and their applications

Prizes and awards

  • 2021 Youth Scholar of“Chang Jiang Scholars Program”

  • 2019 Shanghai Pujiang Talent

  • 2015 Shanghai Rising Star in Science and Technology

Biography

  • 2023.03-            Professor, Department of Chemistry, Fudan University

  • 2018.12-2023.02      Professor, Institutes of Biomedical Sciences, Fudan University

  • 2017.01-2017.12       Visiting Scholar, Department of Biochemistry, Purdue University

  • 2012.12-2018.11       Associate Professor, Institutes of Biomedical Sciences, Fudan University

  • 2009.07-2012.11       Assistant Professor, Institutes of Biomedical Sciences, Fudan University

  • 2004.09-2009.06       PhD, Department of Chemistry, Fudan University

Academic Appointments

  • Member of the Proteomics Committee of the Chinese Society of Biochemistry and Molecular Biology

  • Young Member of the Glycoconjugate Committee of the Chinese Society of Biochemistry and Molecular Biology

  • Member of the Chromatography Committee of the Chinese Association for Testing and Analysis

  • Member of the Mass Spectrometry Committee of the Chinese Association for Testing and Analysis

Teaching activity

  • Basic of Chemical Biology

  • Experiments in analytical chemistry

Key Publications

  • Yang Li, Bin Fu, Maoyu Wang, Weiyu Chen, Jiawei Fan, Yueyue Li, Xuejiao Liu, Zhensheng Zhang*, Haojie Lu*, Ying Zhang* Urinary extracellular vesicle N-glycomics identifies diagnostic glycosignatures for bladder cancer Nat Commun, 2025, 16, 2292.

  • Xin Feng, Ao Shen, Wei Zhang, Shengnan Jia, Anton Iliuk, Yuling Wang, Wenke Zhang, Ying Zhang*, W. Andy Tao*, Lianghai Hu* High-throughput capture and in situ protein analysis of extracellular vesicles by chemical probe-based array. Nat Prot, 2024, https://doi.org/10.1038/s41596-024-01082-z

  • Ting Wang, Yuying Liang, Guoli Wang, Lei Zhang, Haojie Lu*, Ying Zhang*, Ultrafast and chemoselective biotinylation of living cell surface for time-resolved surfaceome analysis. Anal Chem, 2024, 96, 14448-14455

  • Ting Wang, Shiyun Ma, Yang Liu, Lei Zhang, Ying Zhang*, Haojie Lu* A chemical proteomics approach for mapping cell-surface functional lysine in living cell. Nat Commun 2024, 15, 2997

  • Zhenyu Sun, Bin Fu, Guoli Wang, Lei Zhang, Ruofan Xu, Ying Zhang*, Haojie Lu* High-throughput site-specific N-glycoproteomics reveals glyco-signatures for liver disease diagnosis. Nat Sci Rev, 2023, 10, nwac059

  • Zhongjie Wang, Lei Zhang, Wenjuan Yuan, Ying Zhang*, Haojie Lu* SAPT, a fast and efficient approach for simultaneous profiling of protein N- and C-terminome. Anal. Chem., 2021, 93,10553-10560

  • Mayank Srivastava, Ying Zhang*, Jian Chen, Andrew Miller, Devika Sirohi, Yang Zhang, Haojie Lu, Jianqing Xu*, Richard J. Kuhn* and W. Andy Tao* Chemical proteomics tracks virus entry and uncovers NCAM1 as Zika virus receptor. Nat. Comm., 2020, 11, 3896

  • Ying Zhang*, Der-Shyang Kao, Bing Gu, Rajdeep Bomjan, Mayank Srivastava, Haojie Lu, Daoguo Zhou, W. Andy Tao* Tracking pathogen infection by time-resolved chemical proteomics Angew. Chem. Int. Ed., 2020, 59, 2235-2240. (Inside Cover)

  • Lijun Yang, Zhengyu Sun, Lei Zhang, Ye Peng, Yan Cai, Ting Cao, Ying Zhang* and Haojie Lu* Chemical labeling for fine mapping of IgG N-glycosylation by ETD MS. Chem. Sci., 2019, 10, 9302-9307.

  • 《Mass spectrometry-based Chemical Proteomics》 Weiguo Andy Tao and Ying Zhang (专著) Wiley, 2019, ISBN: 9781118970195