MENG GeOrganic Medicinal Chemistry, Professor
Office Location:Engineering Center of Catalysis and Synthesis for Chiral Molecules, Department of Chemistry, Fudan University, No. 220 Handan Road, Shanghai 200433.
Research Group Website:

  • Research Interests

  • Academic Appointments

  • Prizes and awards

  • Biography

  • Teaching

  • Key Publications

  • Target directed design, synthesis and structure-activity relationship of molecules.

  • Design and synthesis of contemporary drugs.

  • Editorial board member of international academic journal : Molbank

  • Reviewer of many academic journals, such as Bioorganic Medicinal Chemistry, Bioorganic Medicinal Chemistry Letter, Journal of Heterocyclic Chemistry, Green Chemistry Letters and Reviews, Mini Reviews in Medicinal Chemistry, etc.

  • 2012,03  Won the Second Award of Shaanxi Higher School Science and Technology for “Research for improving the organic medicinal  intermediates”.

  • 2010,09  Won the Scholarship from Euro-Asia Uninet, Austria.

  • 2007,09  Won the Prize in Bilingual Teaching Contest in Xi’an Jiaotong University, P. R. C.

  • 2003,09  Won the Prize by solving the challenge from Innocentvie, U.S.A.

  • 2017. 6 ~ now  Researcher in Chemistry Department, Fudan University, P. R. China.

  • 2006. 8 ~ 2017. 5 Teacher in School of Medicine, Xi’an Jiaotong University, P. R. China.

  • 2011, 7 ~ 2011.12 Visiting Scholar, Viena University, AUS.

  • 2008,.3 ~ 2009. 3 Postdoctoral Researcher, Michigan Technological University, Michigan, USA.

  • 2004.7 ~ 2006.7 Postdoctoral Researcher, Tsinghua University, Beijing, P. R. China.

  • 1999. 9 ~ 2003. 1 PHD in Organic Medicinal Chemistry, Fudan University, Shanghai, P. R. China.

  • 2001. 7 ~ 2001. 8 Special Training Course in Chemistry, NanKai University, P. R. China.C

  • 1997.9 ~ 1998.1 Visiting Scholar Phytochemistry, Chinese Pharmaceutical University, P. R. China

  • 1992. 9 ~ 1999. 8 Teacher in School of Medicine, Henan University, P. R. China.

  • 1989. 9 ~ 1992. 7 M. S in Pharmaceutical Chemistry, Shandong Medical University, P. R. China.

  • 1985.9 ~ 1989. 7 B. S. Chemistry, Henan University, P. R. China.

  • Fine Organic Synthesis Chemistry

  1. Kaijun Jin, Yali Sang, Erick De Clercq, Christophe Pannecouque, Ge Meng*, Design and synthesis of a novel series of non-nucleoside HIV-1 inhibitors bearing pyrimidine and N-substituted aromatic piperazine. Bioorganic & Medicinal Chemistry Letters 2018, 3491-3495.

  2. Ge Meng*, Meilin Zheng, Mei Wang, et al. Design and synthesis of new potent PTP1B inhibitors with the skeleton of 2-substituted imino-3-substituted-5-heteroarylidene-1,3-thiazolidine-4-one: Part I[J]. Eur. J. Med. Chem., 2016, 122, 756-769.

  3. Ge Meng*, Meilin Zheng, Mengshu Dong,et al.Synthetic optimization of rosiglitazone and related intermediates for industrial purposes[J]. Res. Chem. Intermediat.,2016, 42(3), 2023-2033.

  4. Ge Meng, Meilin Zheng, Meng-shu Dong, et al. An environmental-friendly synthesis of 2,3- disubstituted-2-iminothiazoline-4-ones[J]. J. Heterocyclic Chem., 2016, 53(2): 588-594.

  5. Ge Meng*, Chunyan Liu, Shidong Qin, et al. An improved synthesis of sunitinib malate via a solvent-free decarboxylation process[J]. Res. Chem. Intermediat, 2015, 41, 8941-8954.

  6. Ge Meng*, Yang Liu, A-Qun Zheng, et al. Design and synthesis of a new series of modified CH-diaryl pyrimidines as drug-resistant HIV non-nucleoside reverse transcriptase inhibitors[J]. Eur. J. Med. Chem., 2014, 82, 600-611.

  7. Yang Liu, Ge Meng*, Aqun Zheng, et al. Design and synthesis of a new series of cyclopropyl amino-linking diarylpyrimidines as HIV non-nucleoside reverse transcriptase inhibitors[J].Eur. J. Pharm. Sci., 2014, 62, 334-341.

  8. Ge Meng, Mei Wang, A-Qun Zheng, et al. Efficient one-pot synthesis of ethyl 2-substitued-4- methylthiazole-5-carboxylates[J]. Green Chem. Lett. Rev., 2014, 7(1), 46-49.

  9. Ge Meng, Mei-Lin Zheng, A-Qun Zheng, et al. The novel usage of thiourea nitrate in aryl nitration [J]. Chin. Chem. Lett.2014, 25(1), 87-89.

  10. Ge Meng*, Mei-Lin Zheng, Meng-Shu Dong, et al. An eco-friendly preparation of 2-iminothiazolidin-4-ones derivatives[J]. Org. Prep. Proced. Int., 2012, 44(2), 184-186.

Patent List

1.Ge Meng, Wei-Juan Ge, Yuming Kang, et al. The synthesis of a fused tricyclic quinozoline ring derivetives as anti-heptocarcinoma agents[P]. CN 201610838381X, 2016, 09, 21.

2.Ge Meng, Tao Yang, Jiehe Zhang, et al. The synthesis of a new series of N-1H-Indazole-N’-[4-[2-(N-methylaminocarbonyl)pyridin-4-yl]-oxyphenyl]thioureas and their anti-oxidative and anti-virus activities[P]. CN 2016100321177, 2016, 01,18.

3.Ge Meng, Mei Wang, Wei-Juan Ge, et al. Preparation and usage of 5-(1H-indole-3-methylene)-1,3- thiazolidin-4-one derivatives[P]. ZL 201410240292.6, 2014, 05, 30.

 4.Ge Meng, Juan Shi, Jian-Hua Shi, et al. A new synthesis method of sunitinib[P]. ZL 201410235616.7, 2014, 05, 29.

 5.Ge Meng, Jing Tong, Jian-Hua Shi, et al. The preparation usage recycling of bistribromide-1,3- dipyridinylpropanne[P]. ZL 201410235515.X, 2014, 05, 29.

6.Ge Meng, Tao Yang, Jian-Hua Shi, et al. A transacetylating method from 1-acetyl-4-chloro-1H- indazole to aromatic primary amine [P]. ZL 201410235121.4, 2014, 05, 29.

7.Ge Meng, Da-Zhi Zheng, Dao-Ming Zhang, et al. Method for preparing 2-(4-bromomethyl phenyl)propionic acid based on bi-phase free radical reaction[P]. ZL 201310120520.1, 2013, 04, 09.

8.Ge Meng, Mei-Lin Zheng, Jie Zhang, et al. Preparation of 2-substituted imino-3-substituted-5-(3,5-dimethyl-4-ethoxycarbonyl-1H-pyrrol-2-yl)methylene-4-thiazolidinone derivatives as protein tyrosine phosphatase 1B inhibitors for the treatment of cancer and diabetes[P]. ZL 201210017641.9, 2012, 01, 20.

9.Ge Meng, Mei-Lin Zheng, Jie Zhang, et al. Preparation of 2-substituted imino-3-substituted-5-[4-[2-[N-methyl-N-(2-pyridyl)]amino]ethoxy]benzylidene]thiazolidine-4-one derivatives as protein tyrosine phosphatase 1B inhibitors for treatment of diabetes, cancer, and obesity[P]. ZL 201210017663.5, 2012,01, 20.

10.Ge Meng, Mei Wang, Jan-Hua Shi, et al. Synthesis of new 2-amino-4-methylthiazole-5-carboxylate derivatives [P]. ZL 201110028455, 2011, 01, 27.

Book List

1. Contemporary Drug Synthesis Process [M]. 2015, Xi’an: Xi'an Jiaotong University Press. ISBN: 978-7-5605-6859-9 (651k words). ISBN: in press (Chief Editor).

2. Guidebook to Organic Synthesis [M]. 2009, Beijing: Chemical Industry Press. (490000 words). ISBN: 978-7-122-03159-4. CIP (2008), No. 091131 (Mono-Translator).


Address: Chemistry Building, Department of Chemistry, Fudan University
2005 Songhu Road, Yangpu District, Shanghai 200438, China  Tel: 86-21-31242791
   Copyright © Department of chemistry, Fudan University 2014     Support:WeiCheng