• 肿瘤、糖尿病和心血管等重大疾病的新药研发

• 化学小分子与生物大分子相互作用的研究

• 2014年上海交通大学医学院“九龙医学优秀青年人才奖

• 1999.9-2003.7           浙江师范大学生物系本科，获得理学学士学位

• 2003.9-2008.7           中科院上海药物研究所硕博连读，获得理学博士学位

• 2009.4-2011.12           美国纽约州立大学石溪分校，博士后

• 2012.3-2016.5            上海交通大学医学院，副研究员

• 2016.6-2017.8            上海科技大学，副研究员

• 2017.9起                复旦大学化学系，青年研究员

《化学生物学基础》、《普通化学实验》

1.Bao Cheng, Guirong Zhu, Linghua Meng, Guolin Wu, Qin Chen,* Shengming Ma*. Identification and optimization of biphenyl derivatives as novel tubulin inhibitors targeting colchicine-binding site overcoming multidrug resistance Eur. J. Med. Chem. 2022, 228, 113930.

2.Anni Qin, Hui Qian, Qin Chen,* Shengming Ma*. Palladium-Catalyzed Coupling of Propargylic Alcoholswith Boronic Acids underAmbient Conditions Chin. J. Chem. 2020, 38, 372-382

3.Helin Lu, Guirong Zhu, Tiange Tang, Zhuang Ma, Qin Chen,* Zhilong Chen*. Anticancer Molecule Discovery via C2-Substituent Promoted Oxidative Coupling of Indole and Enolate iScience, 2019, 22, 214-228

4.Lei Ke, Guirong Zhu, Hui Qian, Guangya Xiang, Qin Chen,* Zhilong Chen*.  Catalytic Selective Oxidative Coupling of Secondary N‑Alkylanilines: An Approach to Azoxyarene Org. Lett. 2019, 21, 4008−4013

5.Anni Qin, Guirong Zhu, Qin Chen,* Hui Qian,* Shengming Ma*. Palladium‐Catalyzed Desulfitative Cross‐Coupling Reaction of Sodium Sulfinates with Propargylic Carbonates Adv. Synth. Catal. 2019, 361, 4656-4660

6.Guolin Wu, Bao Cheng, Hui Qian, Shengming Ma, Qin Chen. Identification of HSP90 as a direct target of artemisinin for its anti-inflammatory activity via quantitative chemical proteomics. Org. Biomol. Chem., 2019, 17, 6854-6859 

7.Yuan Yao, Guirong Zhu, Qin Chen,* Hui Qian,* Shengming Ma*  Efficient synthesis of tetrasubstituted 2,3-allenoates and preliminary studies on bioactivities. Org. Chem. Front., 2019, 6, 304-308

8.Xinyu Duan, Pengbin Li,  Guirong Zhu, Chunling Fu, Qin Chen,* Xin Huang,* Shengming Ma*. Pd/Gorlos-Phos-catalyzed cross-coupling between two different aryl chlorides in the presence of B2Pin2 and cytotoxicity studies of the products. Org. Chem. Front. 2018, 5,3319-3323

9.Jiaxin Liu, Longhai Li, Liuzhu Yu, Lisha Tang, Qin Chen,* Min Shi* Visible-Light-Induced Trifluoromethylation of Isonitrile-Substituted Indole Derivatives: Access to 1-(Trifluoromethyl)-4,9-dihydro-3H-pyrido[3,4-b]indole and beta-Carboline Derivatives. Adv. Synth. Catal. 2018, 360:2959  

10.Qin Chen,* Rong Deng, Xian Zhao, Haihua Yuan, Hailong Zhang, Jinzhuo Dou, Ran Chen, Hui Jin, Yanli Wang, Jian Huang, Jianxiu Yu* Sumoylation of EphB1 Suppresses Neuroblastoma Tumorigenesis via Inhibiting PKCγ Activation. Cell Physiol Biochem. 2018, 45(6):2283-2292