Research Interests

• Total Synthesis of Bioactive Compounds

• Medicine Chemistry

• Methodology Development

Prizes and awards

• Thieme Chemistry Journals Award （2017）

• Shanghai Natural Sciences, the First Prize (2011, the fifth participator)

• Presidential Award for the Outstanding Student (Chinese Academy of Sciences, 2009)

Biography

• 1999.9-2004.7         B.S. in ChemistryUniversity of Science and Technology of China

• 2004.9-2009.7         Ph.D. in Chemistry Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences

• 2009.7-2010.1         Research AssociateShanghai Institute of Organic Chemistry, Chinese Academy of Sciences

• 2010.2-2012.3        Postdoctoral Fellowship, Alexander von Humboldt Foundation Technische Universität München, Germany

• 2012.4-2016.5         Postdoctoral FellowshipUniversity of California, Santa Barbara

• 2016.6-                   Principal Investigator   Fudan University

Key Publications

1. Zhonggui Wang,§ Jie Zhu,§ Minyan Wang,* and Ping Lu*, Palladium-Catalyzed Divergent Enantioselective Functionalization of Cyclobutenes, J. Am. Chem. Soc.2024, 146, 12691–12701.

2. Shaowei Wang+, Changxu Zhong+, Yingchao Huang, and Ping Lu*, Enantioselective  Hydrofunctionalization of Cyclobutenones: Total Synthesis of gem-Dimethylcyclobutane Natural Products, Angew. Chem. Int. Ed. 2024, e202400515.

3. Peng Yan, Simone Stegbauer, Qinqin Wu, Elena Kolodzeiski, Christopher J. Stein, Ping Lu,* and Thorsten Bach*, Enantioselective Intramolecular ortho Photocycloaddition Reactions of 2-Acetonaphthones, Angew. Chem. Int. Ed. 2024, 63, e202318126.

4. Min Yan+, Qiang Zhou+, and Ping Lu*, Collective Synthesis of Chiral Tetrasubstituted Cyclobutanes Enabled by Enantioconvergent Negishi Cross-Coupling of Cyclobutenones, Angew. Chem. Int. Ed.2023, 62, e202218008.

5. Peng Yan, Changxu Zhong, Jie Zhang, Yu Liu, Huayi Fang, and Ping Lu*, 3-(Methoxycarbonyl)Cyclobutenone as a Reactive Dienophile in Enantioselective Diels–Alder Reactions Catalyzed by Chiral Oxazaborolidinium Ions, Angew. Chem. Int. Ed.2021, 60, 4609–4613.

6. Changxu Zhong+, Yingchao Huang+, Haocheng Zhang, Qiang Zhou, Yu Liu, and Ping Lu*, Enantioselective Synthesis of 3-Substituted Cyclobutenes by Catalytic Conjugate Addition/Trapping Strategies, Angew.Chem. Int. Ed. 2020, 59, 2750–2754.

7. Meng Wang, Jun Chen, Zongjia Chen, Changxu Zhong, and Ping Lu*, Enantioselective Desymmetrization of Cyclobutanones Enabled by Synergistic Palladium/Enamine Catalysis, Angew. Chem. Int. Ed.2018, 57, 2707–2711.