Research Interests

• Design, synthesis and bioactive evaluation of novel anticancer drugs targeted the tumor microenvironment.

Prizes and awards

• Fuhua Teaching Prize

Biography

• 2004.7-present     Faculty    Department of Chemistry, Fudan University          

• 2010.8-2012.1      Visiting Scholarship   Department of Chemistry and Biochemistry
                  University of Wisconsin-Milwaukee

• 2002.8-2004.7       Postdoctoral Fellow   Department of Chemistry, Fudan Universit

• 2002.7-1999.9       PhD   School of Chemistry and Chemical Engineering, Sun Yat-sen University

• 1999.7-1992.9       M.S. and BSc.   Department of Chemistry, Yunnan University       

Teaching

• Organic Chemistry, Organic Chemistry Laboratory, Synthetic Chemistry Laboratory (I, II)

Key Publications

1. Pan, Xiaolin; Luo, Yong; Kuang, Yunyan*; Li, Guangming*. A facile route to 5-methyl-5H-indeno[1,2-c]quinolones via palladium-catalyzed cyclization of 2-alkynylbromobenzenes with N,N-dimethyl-2-alkynylanilines. Org. Biomol. Chem.,2014, 12(31), 5861-5865.

2. Yunyan Kuang, Huabing Sun, J. Craig Blain, and Xiaohua Peng. Hypoxia-selective DNA interstrand cross-link formation by two modified nucleosides. Chem. Eur. J.,2012, 18, 12609-12613.

3. Yunyan Kuang, Kummudha Balakrishnan, Varsha Gandhi, and Xiaohua Peng. Hydrogen peroxide inducible DNA cross-linking agents: targeted anticancer prodrugs. J. Am. Chem. Soc., 2011, 133, 19278-19281.

4. Yunyan Kuang, Jingze Niu, Fener Chen. Total Synthesis of (20S)-7-ethyl-10-hydroxy camptothecin via a bifunctional thiourea-based cinchona alkaloid-mediated enantioselective cyanosilylation strategy. Helvetica Chimica Acta, 2010, 93, 2094-2099.

5. Kuang Yunyan, Chen Fener. Copper- and Phosphine-Free Sonogashira Coupling Reaction Catalyzed by Polyurea-Encapsulated Palladium (II). Helvetica Chimica Acta, 2009, 92(5), 897-902.