EN
Qiuqin He
Organic Chemistry
Associate Professor
qqhe@fudan.edu.cn
Room A7019, Chemistry Building, Department of Chemistry, Fudan University 2005 Songhu Road, Yangpu District, Shanghai 200438, China
86-21-3124
Research Interests
Small molecule drugs R & D
New methodologies for synthetic drugs
Prizes and awards
The Second prize for progress in science and technology of Shanghai (2013)
Biography
2012.09-now Department of Chemistry, Fudan University, Lecturer
2009.10-2012.09 Department of Chemistry, Fudan University, Post-doctor
2007.06-2009.10 Shanghai Chempartner Co. Ltd., Team Leader
2002.09-2007.06 Second Military Medical University, Ph.D
1998.09-2002.06 China Pharmaceutical University, Bachelor degree
Teaching
Medicinal Chemistry
Experiment of synthetic chemistry
Key Publications
Hai-Qiu Wu, Christophe Pannecouque, Zi-Hong Yan, Wen-Xue Chen, Qiu-Qin He*, Fen-Er Chen,* Jan Balzarini, Dirk Daelemans and Erik De Clercq. Synthesis and biological evaluation of new conformationally restricted S-DABO hybrids as non-nucleoside inhibitors of HIV-1 reverse transcriptase. Med. Chem. Commun.,5 (2014) 468–473.
Zi-Hong Yan, Xia-Yun Huang, Hai-Qiu Wu, Wen-Xue Chen, Qiu-Qin He*, Fen-Er Chen, Erik De Clercq, Christophe Pannecouque. Structural modifications of CH(OH)-DAPYs as new HIV-1 non-nucleoside reverse transcriptase inhibitors. Bioorg. Med. Chem., 22 (2014) 2535–2541.
Le-Meng Hu, Fang-Jun Xiong, Xiao-Fei Chen, Wen-Xue Chen, Qiu-Qin He*, Fen-Er Chen*. Synthetic studies on statins. Part 1: a short and cyanide-free synthesis of atorvastatin calcium via an enantioselective aldol strategy. Tetrahedron: Asymmetry 24 (2013) 207–211.
Shuang-Xi Gu, Zhi-Ming Li, Qiu-Qin He*, Fen-Er Chen*, Erik De Clercq, Jan Balzarini, Christophe Pannecouque. Chiral resolution, absolute configuration assignment and biological activity of racemic diarylpyrimidine CH(OH)-DAPY as potent nonnucleoside HIV-1 reverse transcriptase inhibitors. Eur. J. Med. Chem., 53 (2012), 229-234.
Qiu-Qin He, Shuang-Xi Gu, Jia Liu, Hai-Qiu Wu, Xuan Zhang, Liu-Meng Yang, Yong-Tang Zheng, Fen-Er Chen*. Structural modifications of quinolone-3-carboxylic acids with anti-HIV activity. Bioorg. Med. Chem., 19 (2011), 5039-5045.
