EN
Haojie Lu
Analytical Chemistry
Professor
luhaojie@fudan.edu.cn
Room 311 Mingdao building, 131 Dong'an
86-21-54237618
Research Interests
Novel mass spectrometric technologies for separation and identification of low-abundance proteins and post-translational proteins
Novel mass spectrometric technologies for relative and absolute quantification of proteome
Novel mass spectrometric technologies for profiling of biomarker for disease tissue
Prizes and awards
2005 Winner of the first prize of Education Ministry of Natural Science Prize nomination (fourth)
2005 Winner the Century Star from Fudan University（comprehensive）
2006 Winner of Education Ministry's New Century Excellent Talents Supporting Plan
2006 Sponsored by Shanghai Rising-Star Program
2008 Sponsored by Shanghai Shuguang scholars Fund
2008 Obtained the Meiji dairy life science Excellence Award
2009 Winner of Young chemist Award from China Chemical Society
2009 Awarded as the university distinguished professor of Shanghai (Eastern Scholar)
2010 Supported by The National Science Fund for Distinguished Young Scholars
2013 Awarded the Eastern Scholar tracking program
Biography
1992.09-1996.07 Xiamen University obtained a Bachelor's degree
1996.09-2001.07 Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences， obtained Ph.D
2001.09-2003.07 Shanghai Institute of Organic Chemistry, Chinese Academy of Science, postdoctoral
2003.09-present Department of Chemistry and Institutes of Biomedical Sciences, Fudan University, assistant professor, associate professor and professor
2006.09-2007.09 School of Medicine at University of California, Los Angeles (UCLA), visiting scholar
Teaching
Analytical chemistry、New technology and new method of proteomics
Key Publications
Yang Lijun, Sun Zhenyu, Zhang Lei, Cai Yan, Peng Ye, Cao Ting, Zhang Ying* and Lu Haojie*, Chemical labeling for fine mapping of IgG N-glycosylation by ETD-MS.Chem Sci, 2019, 10(40): 9302-9307
Zhang Siwen, Fang Caiyun, Yuan Wenjuan, Zhang Ying, Yan Guoquan, Zhang Lei, Di Yi, Cai Yan and Lu Haojie*, Selective identification and site-specific quantification of 4-Hydroxy-2-nonenal-modified proteins. Anal Chem, 2019, 91(8): 5235-5243
Di Yi, Zhang Lei, Zhang Ying, Zhao Huanhuan, Yan Guoquan, Yao Jun, Zhang Shu and Lu Haojie*, MdCDPM: A mass defect-based chemical-directed proteomics method for targeted analysis of intact sialylglycopeptides. Anal Chem, 2019, 91(15): 9986-9992
Di Yi, Zhang Ying, Zhang Lei, Tao Tao, Lu Haojie* MdFDIA: A mass defect based four-plex data-independent acquisition strategy for proteome quantification. Anal Chem, 2017, 89(19): 10248–10255
Yuan Wenjuan, Zhang Ying, Xiong Yun, Tao Tao, Wang Yi, Yao Jun, Zhang Lei, Yan Guoquan, Bao Huimin, Lu Haojie*. Highly selective and large scale mass spectrometric analysis of 4-Hydroxynonenal modification via fluorous derivatization and fluorous solid-phase extraction. Analy Chem, 2017, 89(5): 3093-3100
Xiong Yun, Zhang Ying, Yao Jun, Yan Guoquan, Lu Haojie*. Direct digestion of living cells via a gel-based strategy for mass spectrometric analysis.Chem Commun, 2017, 53(8): 1421-1424
Zhang Ying, Zhang Cheng, Jiang Hucong, Yang Pengyuan, Lu Haojie *. Fishing the PTM proteome with chemical approaches using functional solid phases. Chem Soc Rev, 2015, 44(22): 8260-8287
Liu Minbo, Fang Caiyun, Pan Xiuwen, Jiang Hucong, Zhang Lijuan, Zhang Lei, Zhang Ying, Yang Pengyuan, Lu Haojie *. Positive enrichment of C-terminal peptides using oxazolone chemistry and biotinylation. Anal Chem, 2015, 87(19): 9916-9922
Ma Wanfu, Zhang Ying, Li Lulu, You Lijun, Zhang Peng, Zhang Yuting, Li Jumei, Yu Meng, Guo Jia, Lu Haojie *, Wang Changchun*. Tailor-made magnetic Fe3O4@mTiO2 microspheres with a tunable mesoporous anatase shell for highly selective and effective enrichment of phosphopeptides. ACS Nano, 2012, 6(4):3179-3188
