EN
Haojie Lu
Analytical Chemistry
Professor
luhaojie@fudan.edu.cn
Room 311 Mingdao building, 131 Dong'an
86-21-54237618
Research Interests
Novel mass spectrometric technologies for separation and identification of low-abundance proteins and post-translational proteins
Novel mass spectrometric technologies for relative and absolute quantification of proteome
Novel mass spectrometric technologies for profiling of biomarker for disease tissue
Prizes and awards
2005 Winner of the first prize of Education Ministry of Natural Science Prize nomination (fourth)
2005 Winner the Century Star from Fudan University（comprehensive）
2006 Winner of Education Ministry's New Century Excellent Talents Supporting Plan
2006 Sponsored by Shanghai Rising-Star Program
2008 Sponsored by Shanghai Shuguang scholars Fund
2008 Obtained the Meiji dairy life science Excellence Award
2009 Winner of Young chemist Award from China Chemical Society
2009 Awarded as the university distinguished professor of Shanghai (Eastern Scholar)
2010 Supported by The National Science Fund for Distinguished Young Scholars
2013 Awarded the Eastern Scholar tracking program
Biography
1992.09-1996.07 Xiamen University obtained a Bachelor's degree
1996.09-2001.07 Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences， obtained Ph.D
2001.09-2003.07 Shanghai Institute of Organic Chemistry, Chinese Academy of Science, postdoctoral
2003.09-present Department of Chemistry and Institutes of Biomedical Sciences, Fudan University, assistant professor, associate professor and professor
2006.09-2007.09 School of Medicine at University of California, Los Angeles (UCLA), visiting scholar
Teaching
Analytical chemistry、New technology and new method of proteomics
Key Publications
Li Zhonghua*, Du Qi, Feng Xiaoxiao, Song Xuezheng, Ren Zhenggang, Lu Haojie * A One-Step Enzymatic Strategy for Efficient Imaging and Mapping of Tumor- Associated Tn Antigen. J Am Chem Soc, 2024, 146, 30, 20539–20543
Wang Ting, Ma Shiyun, Ji Guanghui, Wang Guoli, Liu Yang, Zhang Lei, Zhang Ying * and Lu Haojie* A Chemical proteomics approach for global mapping of functional lysines on cell surface of living cell. Nat Commun, 2024, 15, 2997,
Xiong Yingying, Lu Zhuoer, Shao Yuyin, Meng Peiyi, Wang Guoli, Zhou Xinwen, Yao Jun, Bao Huimin*, and Lu Haojie* Multifunctional materials enable ultrafast and large-scale enrichment of glycopeptides and reveal distinct spatial patterns upon oxidative stress. Nat Sci Rev, 2024, DOI:10.17632/2v8zncksb2.1
Sun Zhenyu, Fu Bin, Wang Guoli, Zhang Lei, Xu Ruofan, Zhang Ying *, Lu Haojie * High-throughput site-specific N-glycoproteomics reveals glyco-signatures for liver disease diagnosis. Nat Sci Rev, 2023, 10, nwac059
Cheng Mengxia, Shu Hong, Yang Maohua, Yan Guoquan, Zhang Lei, Wang, Liang Wang Wenning, and Lu Haojie* Fast discrimination of sialylated N-Glycan linkage isomers with one-step derivatization by microfluidic capillary electrophoresis-mass spectrometry. Anal Chem, 2022, 94(11), 4666–4676.
Yang Lijun, Sun Zhenyu, Zhang Lei, Cai Yan, Peng Ye, Cao Ting, Zhang Ying* and Lu Haojie*, Chemical labeling for fine mapping of IgG N-glycosylation by ETD-MS. Chem Sci, 2019, 10(40): 9302-9307
Zhang Siwen, Fang Caiyun, Yuan Wenjuan, Zhang Ying, Yan Guoquan, Zhang Lei, Di Yi, Cai Yan and Lu Haojie*, Selective identification and site-specific quantification of 4-Hydroxy-2-nonenal-modified proteins. Anal Chem, 2019, 91(8): 5235-5243
Di Yi, Zhang Lei, Zhang Ying, Zhao Huanhuan, Yan Guoquan, Yao Jun, Zhang Shu and Lu Haojie*, MdCDPM: A mass defect-based chemical-directed proteomics method for targeted analysis of intact sialylglycopeptides. Anal Chem, 2019, 91(15): 9986-9992
Zhang Ying, Zhang Cheng, Jiang Hucong, Yang Pengyuan, Lu Haojie *. Fishing the PTM proteome with chemical approaches using functional solid phases. Chem Soc Rev, 2015, 44(22): 8260-8287
Ma Wanfu, Zhang Ying, Li Lulu, You Lijun, Zhang Peng, Zhang Yuting, Li Jumei, Yu Meng, Guo Jia, Lu Haojie*, Wang Changchun*. Tailor-made magnetic Fe3O4@mTiO2 microspheres with a tunable mesoporous anatase shell for highly selective and effective enrichment of phosphopeptides. ACS Nano, 2012, 6(4):3179-3188
