刘小文

有机化学

青年研究员,硕士生导师

liuxw@fudan.edu.cn

复旦大学手性分子催化与合成工程中心A212室

研究兴趣

  • 蛋白稳定化研究

  • 难溶性药物增溶

学习工作经历

  • 2022.10- 至今   复旦大学化学系,青年研究员

  • 2020.10-2022.9   暨南大学基础医学与公共卫生学院,副教授

代表性论文或专著

  • X. Liu*, J Chen, J. Zhong, F. Chen*. Tailored amphiphilic polymers enable stabilized biologics in hyperthermal water and freeze-drying process. Chem. Eng.J., 2024, 482, 148962

  • X. Xin, Y. Liu, L. Guo, H.Wang, D. Lu, Y. Chang, M. Wan, Y. Zhang, Y. Shan, Q. Zhang, X. Liu*, F. Gao*. Improvement of B cell responses by an HIV-1 amphiphilic polymer nanovaccine. Nano Lett., 2023, 23, 9, 4090–4094

  • X. Liu*, L. Zhao, B. Wu, F. Chen*. Improving solubility of poorly water-soluble drugs by protein-based strategy: a review. Int. J. Pharm., 2023, 634,122704.

  • X. Xin, J. Chen, L. Chen, J. Wang, X. Liu*, F. Chen*. Lyophilized insulin micelles for long-term storage and regulation of blood glucose for preventing hypoglycemia. Chem. Eng.J., 2022, 435, 134929.

  • P. Zhou, X. Zhang, X. Xin, J. Yang, Q. Pan, C. Liu, Y. Liu, X. Yu, Z. Li*, G. Jiao*, X. Liu *. Click chemistry-conjugated protein-drug micelles with anti-ferroptotic and anti-inflammatory properties promote regeneration in spinal cord injury. Chem. Eng.J., 2022, 428, 132118.

  • X. Xin, Y. Xu, H. Shi, X. Liu*. General method to stabilize mesophilic proteins in hyperthermal water. iSciecne, 2021, 24 (5), 102503.

  • X. Liu, P. Zhang, D. He, W. Rodl, T. Preiß, J. O.Radler, E. Wagner, U. Lächelt*. pH-reversible cationic RNase A conjugates for enhanced cellular delivery and tumor cell killing. Biomacromolecules, 2016, 17(1), 173-182.